Alzheimer-Genetics

Alzheimers is a genetic mutauion. It can be passed on to children. People with down's syndrome are know to develop alzheimer's. Chromosome 21 is a mutated gene that is associated with Familial Alzheimer's disease(FAD) and Alzheimers disease(AD). Genetic defect caused the formation of a defective amyloid protein. The defective amyloid protein is deposited in certain places in the cerebral cortex. It destroys neurons and produces the clinical symptoms of AD In a very few families, people develop alzheimer's disease in there 30s, 40s, 50s. Many of these people have a mutation,or mermanent changes, in one of three genes that they inherited from a parent. Most people with alzheimer's disease have late-onset Alzheimer's, which usually developes after age 60. many studies have linked a gene called APOE to late-onset alzheimer's. The only cause of death among the top 10 in the united states that cannot be prevented, cured or even slowed. Alzheimers is the sixth leading cause of death in the country.
 * __Alzheimer’s Genetics __**

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